http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4942165-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42ac502ee7968fb28fcdadf16f92dda7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-559 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 1988-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efef8f6a266ee3d97c09a5368fb01f9f |
| publicationDate | 1990-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4942165-A |
| titleOfInvention | Treatment for Alzheimer's disease |
| abstract | Hydropyridine analogs, dihydropyridine analogs, trihydropyridine analogs, hydropurine analogs, dihydropurine analogs, trihydropurine analogs, N,N,N,'-trimethyl- N'-(2-hydroxy-3-methyl-1,3-propanediamone analogs, 1-methyl-3-[N-(4-iodophenyl)- carbamoyl]-1,4-dihydropyridine analogs, that are lipid-soluble with the specific electron charge density and therefore useful for the administration of several compounds that need to penetrate the blood-brain capillary barrier. Once inside the brain these compounds undergo NAD-NADH reduction thereby providing for a brain serum retention. These compounds having been modified herein to deliver various compounds, some of which are those that are progressively absent during the course of a disease called Alzheimer's Disease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010216875-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004058852-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008227806-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007038772-A1 |
| priorityDate | 1986-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 234.