http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4935536-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc365d0d4cf537a503859144cd924ad6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-066 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 |
filingDate | 1989-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1990-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2b9ac4ddfa48eeb1cc37988f6ff55f |
publicationDate | 1990-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4935536-A |
titleOfInvention | Protecting groups for asparagine and glutamine in peptide synthesis |
abstract | Trialkoxybenzyl (Taob) protected asparagine and glutamine, a method of synthesis and a method of use are provided. The Taob protected Asn and Gln have the following formulae: <IMAGE> or <IMAGE> wherein Z is an alkyl group having from 1 to 10 carbon atoms; X and W are any alpha -protecting group which can be selectively removed while maintaining Taob intact; Y is H or any group sufficiently active or activatable to react with NH2- or NH= to generate an amide bond; n is 1 for asparagine or 2 for glutamine. These derivatives are stable in solution, have good solubility in organic solvents and couple directly without side reactions. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5189088-A |
priorityDate | 1987-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.