http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4933442-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42d31351c76b18378e315027a536c70e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-108 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-108 |
| filingDate | 1989-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f7a1f77ace0d2c496412b5458b36fb7 |
| publicationDate | 1990-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4933442-A |
| titleOfInvention | 1-(acetylaminophenyl)-2-aminopropanone derivatives and central nervous system antidepressant compositions |
| abstract | The present invention relates, by way of new industrial products, to 1-(acetylaminophenyl)-2-amino-propanone derivatives selected from the group consisting of n (a) the compounds of the formula n n Ar--CO--CH(CH.sub.3)--NR.sub.1 R.sub.2 (I) n n in which n R 1 represents a C 1 -C 4 alkyl group or a C 3 -C 6 cycloalkyl group; n R 2 represents the hydrogen atom or a C 1 -C 4 alkyl group; n R 1 and R 2 , taken together, can form, with the nitrogen atom to which they are bonded, an N-heterocyclic group with 5 to 7 ring members, capable (i) of including a second heteroatom selected from N, O and S, and (ii) of being substituted, the said heterocyclic group NR 1 R 2 being selected from the group comprising pyrrolidino, morpholino, thiomorpholino, piperidino, hexamethyleneimino, piperazino, 4-methylpiperazino, 4-(β-hydroxyethyl) piperazino, 4-phenylpiperazino and 4-(p-chlorophenyl)-piperazino groups; and n Ar represents an acetylaminophenyl group of the formula ##STR1## in which X is CH 3 CONH and Y and Z, which can be identical or different, each represent a hydrogen or halogen atom; and n (b) their addition salts. n These new products are useful in therapy. n The invention also relates to the method for their preparation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5236922-A |
| priorityDate | 1983-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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