http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4933290-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47becd0bad1e8c65826be1edac09d306 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-14 |
| filingDate | 1987-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78c2beb9c3976046336ce929eb0c6474 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_385d9a2e92ac5cb552b2fbd53efd0be6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a764248315f1385ea0f5f4f4fc465caf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4e6f0db11701f623aea76c561a36f34 |
| publicationDate | 1990-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4933290-A |
| titleOfInvention | Process for the enzymatic separation of the optical isomers of racemic oxazolidinonic derivatives |
| abstract | A process for the separation of a racemic mixture of the S(+) and R(-) optical isomers of an oxazolidinone compound of the formula: <CHEM> (in which R is a straight or branched C1-C8 alkyl group) which process comprises reacting the racemic 3-alkyl-5-hydroxy-methyl-oxazolidin-2-one derivative of formula (I) with an esterifying compound which is (a) an ester of the formula: <CHEM> (in which R' is a straight or branched C1-C10 alkyl or alkenyl group, and R'' is a straight or branched C1-C4 alkyl or alkenyl group, a haloalkyl group or a diacylglycerolic group), (b) an acid of the formula: R'''-COOH (V) (in which R''' is a straight or branched C1-C20 alkyl or alkenyl group) or (c) an anhydride of the formula: <CHEM> (in which R<IV> is a straight or branched C1-C6 alkyl group) the reaction being carried out in the presence of an enzyme, immobilized on a porous carrier, capable of selectively giving rise to the esterification of the R(-) isomer, while leaving the S(+) isomer of the racemic starting compound of formula (I) substantially unchanged; and separating the S(+) isomer. > |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5494821-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5106750-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5156962-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5942527-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5037747-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5061629-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5037759-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5110943-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5326885-A |
| priorityDate | 1986-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 166.