| abstract |
New Sulphonamides of the formula: <IMAGE> (I) wherein R1 and R2, which can be the same or different, are hydrogen or halogen atoms, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkylthio, C1-C6-alkylsulphinyl, C1-C6-alkylsulphonyl or trifluoromethyl radicals or hydroxyl or cyano groups, R3 and R8, which can be the same or different, are hydrogen atoms, C1-C6-alkyl, benzyl or C1-C6-alkanoyl radicals, R4 and R5, which can be the same or different, are hydrogen atoms or C1-C6-alkyl radicals, R6 and R7 are both hydrogen atoms or together form a valency bind, X is an oxygen or sulphur atom or an =NOH or =NR8 group and n is a whole number of from 1 to 4; and the physiologically acceptable salts thereof with inorganic and organic bases. These compounds are useful for example in the treatment of asthma or cardiovascular disease, thrombosis prevention and treatment, and to combat broncoconstriction. |