| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79751aeaa9923745648e5ae7d9c35782 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-98 |
| filingDate |
1988-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1990-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfae16f596bf9169a5da5686fa1334af |
| publicationDate |
1990-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4923993-A |
| titleOfInvention |
Process for the preparation of 2-pyridinecarboxylic acid derivatives and 1-amino-1,4-dihydropyridine-2-carboxylic acid derivatives |
| abstract |
The process of the invention relates to the reaction of hydrazones of formula II ##STR1## with α-chloro- or α-bromoarylonitrile or α-chloro- or α-bromoacrylates of formula III ##STR2## to 1-amino-2-cyano-1,4-dihydropyridines or 1-amino-1,4-dihydropyridine-2-carboxylic acid esters of formula IV ##STR3## which are converted into pyridine derivatives of formula I ##STR4## by treatment with an acid, with removal of R 4 R 5 NH. Y is --CN or --COOR 3 and R 1 to R 5 may be alkyl. |
| priorityDate |
1985-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |