Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
filingDate |
1989-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1990-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf18077a89573d7c45660d3455fd52e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43b07f6f50e2aee2fd0eb414fc813958 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8043c3660f369a10a36415466c0a9d84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91373e016010ed1fee70d89f9efa5e8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ea45cd80f9d955df0167686da0f4d62 |
publicationDate |
1990-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4914200-A |
titleOfInvention |
Process for preparing 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives |
abstract |
A process for preparing a 4-acetoxy-3-hydroxyethylazetidin-2-one derivative having the formula (II): ##STR1## wherein R 1 is a protective group for the hydroxyl group, which comprises reacting a β-lactam compound having the formula (I): ##STR2## wherein R 1 is as defined above, and R 2 , R 3 and R 4 are a lower alkyl group having 1 to 6 carbon atoms, phenyl group or an aralkyl group, with acetic anhydride in an organic solvent in the presence of a low concentration of a substituted pyridine. According to the present invention, there can be obtained 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives, which are useful intermediates for preparing carbapenem β-lactam antibiotics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014097257-A1 |
priorityDate |
1986-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |