abstract |
An antibacterial 7beta-(carboxyalkenoyl)amino-3-cephem-4-carboxylic acid represented by the following formula: ##STR1## (wherein R is aryl or a heterocyclic group; n R 1 is hydrogen or halogen; n R 2 is a single bond, alkylene, or thiaalkylene; n R 3 is a hydrogen atom or carboxy modifying group; n R 4 is hydrogen or methoxy; n R 5 is hydrogen or a 3-substituent of cephalosporins; n R 6 is a hydrogen atom or carboxy modifying group; and n X is oxygen, sulfur, or sulfinyl) n a pharmaceutical composition containing the same, and a method for treating a bacterial infection with the same. |