| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4819c818db97dcad44665c6fad44d3e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-18 |
| filingDate |
1987-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1990-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d03c137f6a9f7d16c583e3aac828ff25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8f2c7fea21fbd79cec277d469a7c628 |
| publicationDate |
1990-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4908309-A |
| titleOfInvention |
Method of detecting cysteine proteases |
| abstract |
Peptide thioneamides are provided as synthetic substrates for cysteine proteases. The compounds of the invention are peptides consisting of one or more blocked or unblocked amino acids wherein the terminal carboxy of the peptides are thionated and forms a thioneamide linkage with a fluorogenic or chromogenic leaving group. The alpha carbonyls of the remaining amino acids are thionated or unthionated. The invention includes methods and kits for using the peptide thioneamides. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9616167-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010249427-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8071328-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008268482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9909208-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8227205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8476036-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8715950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5776718-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009275051-A1 |
| priorityDate |
1986-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |