http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4900737-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 |
| filingDate | 1988-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9707e915cc809197b564e32b6d15edca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de5597a782c238a8722c8c96dc3920c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2be35dd27ca932e88083b2a32f72fd00 |
| publicationDate | 1990-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4900737-A |
| titleOfInvention | Isoquinoline derivatives |
| abstract | Compounds of formula (I) <IMAGE> (wherein R1 is a hydrogen atom or a methyl group; R2 is a hydrogen atom or a hydroxyl, C1-4 alkoxy or C2-4 alkanoyloxy group; R3 is a hydrogen atom, or (when R2 is other than a hydrogen atom) optionally a hydroxyl, C1-4 alkoxy or C2-4 alkanoyloxy group, or R2 and R3 together are a methylenedioxy group; R4 is a hydrogen or halogen atom or a methyl group; R5 and R6 is each a hydrogen atom or a group -OCOCH2NR7R8 [where R7 and R8, which may be the same or different, each is a hydrogen atom or a C3-7 cycloalkyl group or a straight or branched C1-4 alkyl group optionally substituted by a hydroxyl group, or -NR7R8 forms a saturated heterocyclic amino group which has 5-7 ring members and optionally contains in the ring an oxygen or sulphur atom or a group -NH- or -N(R) where R is a C1-4 alkyl group optionally substituted by a hydroxyl group] with the proviso that when one of R5 and R6 is a hydrogen atom, the other is a group -OCOCH2NR7R8) may be prepared by amination of a corresponding compound where R5 and/or R6 is a group -OCOCH2L wherein L is a displaceable leaving group. The compounds of formula (I) and their physiologically acceptable salts exhibit interesting cancer combatting properties. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100460785-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805204-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114805204-A |
| priorityDate | 1985-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.