http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4891371-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4655b70cbfba352025a1d2393b449e77 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1988-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1990-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82d47e3851d9c6915e766c54b97af0e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6fde39f988444143b75487f1e59c55b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6210dba926ab65332accd9ded7cdd857 |
| publicationDate | 1990-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4891371-A |
| titleOfInvention | 3-(Acylaminomethyl)imidazo[1,2-a]pyridine derivatives, their preparation and their application in therapy |
| abstract | A compound which is a 3-(acylaminomethyl)imidazo[1,2-a]pyridine derivative of formula (I) ##STR1## in which R 1 denotes hydrogen; linear or branched C 1 -C 4 alkyl; or benzyl: n R 2 denotes linear or branched C 1 -C 6 alkyl; cyclohexyl; trichloromethyl; 1-propenyl; allyl; phenyl; 4-chlorophenyl; or benzyl; or R 1 and R 2 together denote a C 3 -C 5 aliphatic chain: n X denotes halogen; C 1 -C 3 alkyl; methylthio; trifluoromethyl; optionally esterified carboxy of formula --COOR in which R denotes hydrogen or C 1 -C 6 alkyl; cyano; optionally mono- or dialkylated aminocarbonyl of formula --CONR 3 R 4 in which R 3 and R 4 independently denote hydrogen or C 1 -C 4 alkyl or together denote a chain of formula --(CH 2 ) 2 --Z--(CH 2 ) 2 -- in which Z denotes a direct bond, oxygen, sulphur, or a divalent group of formula --CH 2 --, --NH--or --N(C 1 -C 4 alkyl)--; alkylamino of formula NHR 5 in which R 5 denotes C 2 -C 6 alkyl; or dialkylamino of formula --NR 6 R 7 in which R 6 R 7 independently denote C 2 -C 6 alkyl or together denote a chain of formula --(CH 2 ) 2 --Z--(CH 2 ) 2 -- in which z denotes a direct bond, oxygen, sulphur, or a divalent group of formula --CH 2 --, --NH-- or --N(C 1 -C 4 alkyl)--: and Y denotes hydrogen; halogen; methyl; trifluoromethyl; optionally esterified carboxy of formula --COOR 8 in which R 8 denotes hydrogen or C 1 -C 6 alkyl; cyano; optionally mono- or dialkylated aminocarbonyl of formula --CONR 9 R 10 in which R 9 and R 10 independently hydrogen or C 1 -C 4 alkyl; or optionally mono- or dialkylated amino of formula --NR 11 R 12 in which R 11 and R 12 independently denote hydrogen or C 1 -C 4 alkyl: with the exclusion of compounds in which X denotes halogen; alkyl; or methylthio and Y denotes hydrogen; halogen; or methyl; n or a pharmacologically acceptable acid addition salt is useful in therapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5614531-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5668286-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913737-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9309238-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9908876-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012220457-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6379649-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10919888-B2 |
| priorityDate | 1986-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 273.