http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4889926-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3e44e8a7bad23cd72efd76db5bde60b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-252 |
| filingDate | 1988-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a46bab678cf689957ff7b626277cec4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5085fe92aef052f5edae2c77052f11fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20584eac8b71ba6521ce63bbc34b8fe0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_464dee99029447d6499bb6e8afb6eac2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f942afe3b08088d48ab08ca8e749dcc |
| publicationDate | 1989-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4889926-A |
| titleOfInvention | Method for the synthesis of (2"R)-4'-O-tetra-hydropyranyladriamycim using 14-chloro-daunomycin as an intermediate |
| abstract | A new compound, i.e., 14-chlorodaunomycin, and its method of preparation are provided. The new compound, useful as an antitumor agent and as an intermediate in the preparation of (2"R)-4'-O-tetrahydropyranyladriamycin, is obtained by reaction of daunomycin with an alkyl ortho-formate and a brominating agent to produce a 14-bromo-13-dialkylketaldaunomycin, hydrolysis of the latter compound, then adding an excess of a solid metal/chloride to produce an acid addition salt of 14-chlorodaunomycin and concurrently salting out the latter compound from the reaction solution, followed by recovering the 14-chlorodaunomycin acid addition salt. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111675738-A |
| priorityDate | 1987-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.