abstract |
Liposome composition is prepared by freezing liposomes in which a hydrophilic drug and one or more members selected from the group consisting of glucose, galactose, mannose, maltose and maltotriose are entrapped, in the presence of the aqueous solution of one or more members selected from the group of said saccharides. Thus obtained composition can be stably stored under freezing condition, and at thawing treatment, the leakage amount of the hydrophilic agent is exceedingly small. |