http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4876267-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-16 |
| filingDate | 1987-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33ea2f69a5c0dca47f4fa50de77547a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02ed384e744a65c31ebfad709f2684e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58a9835be9e35c5a911ed09ece35dc01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d931be1dffa420d986536063e537f327 |
| publicationDate | 1989-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4876267-A |
| titleOfInvention | 5-Aminosulphoryl substituted indole derivatives |
| abstract | Indole derivatives are disclosed of the formula (I): <IMAGE> (I) wherein R1 represents H, or C1-6 alkyl or C3-6 Alkenyl; R2 represents a H, C1-3 alkyl, C3-6 alkenyl or C5-7 cycloalkyl, or a phenyl or phen(C1-4)alkyl group in which the phenyl ring is optionally substituted by halogen or C1-3 alkyl, C1-3 alkoxy or hydroxyl, or by a group NRaRb, or CONRaRb, wherein Ra and Rb each independently represents H or C1-3 alkyl; R3 and R4, each independently represents H or C1-3 alkyl or 2-propenyl; and physiologically acceptable salts and solvates (e.g. hydrates) thereof. The compounds have potent and selective vasoconstrictor activity and are indicated as useful for the treatment of migraine. The compounds may be formulated as pharmaceutical compositions with pharmaceutically acceptable carriers or excipients for administration by any suitable means. Various methods for the preparation of the compounds are disclosed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6521658-B1 |
| priorityDate | 1986-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 237.