http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4870189-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f88f84fc279fe5d0b9b5ec3c88c2e2b2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-04 |
| filingDate | 1987-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc7654d2a0a428ffae5117f7120703a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b94026b56f94028c029c891c62fde8e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_322feee405794c458c99fb427506077b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1a6637b51f116d57a924586425dae3c |
| publicationDate | 1989-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4870189-A |
| titleOfInvention | Process for synthesis of azetidine and novel intermediates therefor |
| abstract | A novel process is described for preparing azetidine and 2 or 3 methyl and ethyl azetidine free bases by reacting primary arylmethylamine having suitable bulk providing substituents attached to the methyl carbon and an appropriate propane derivative having leaving groups in the one and three position in hot organic solvent containing a non-nucleophilic base and an amount of water sufficient to promote azetidine ring formation to give N-protected-azetidines and deprotecting by hydrogenolysis under acidic conditions to give an acid salt of the azetidines and thereafter flashing off vaporized azetidine from a hot, agitated strong base solution or slurry and condensing to give the liquid azetidine free bases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6506907-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100395779-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6333418-B1 |
| priorityDate | 1987-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.