http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4855453-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ede6dfd510f800f051b3578956a2999 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-80 |
| filingDate | 1988-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b683eeb8bb44d7163abb44c345b6d8d |
| publicationDate | 1989-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4855453-A |
| titleOfInvention | Tetracyclic thiophene derivatives |
| abstract | The present invention relates to anti tumor compounds of formula (I) ArCH2R1 (I) or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 29 carbon atoms in total); ethers, esters thereof; acid addition salts thereof; wherein Ar is a fused tetracyclic aromatic ring system comprised of 5-membered and 6-membered rings and contains at least one heteroatom and 3 aromatic rings and a total of no more than 18 ring atoms, or a substituted derivative thereof; the heteroatom is preferably oxygen, sulfur or nitrogen; when it is nitrogen this is substituted by hydrogen, methyl or ethyl; R1 contains not more than eight carbon atoms and is a group <IMAGE> wherein m is 0 or 1; R5 is hydrogen; R6 and R7 are the same or different and each is hydrogen or C1-5 alkyl optionally substituted by hydroxy; R8 and R9 are the same or different and each is hydrogen or C1-3 alkyl; <IMAGE> is a five or six-membered saturated carbocyclic ring; R10 is hydrogen, methyl or hydroxymethyl; R11, R12 and R13 are the same or different and each is hydrogen or methyl; R14 is hydrogen, methyl, hydroxy, or hydroxymethyl. |
| priorityDate | 1985-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 365.