| abstract |
Derivatives of 3-acylamino-3-deoxyallose represented by the following formula: ##STR1## wherein R 1 , R 2 , R 3 and R 4 may be hydrogen atoms, or R 1 and R 2 , and R 3 and R 4 may be in combination an isopropylidene group, R 5 represents a hydrogen atom or alkyl group, and R 6 represents a hydrogen atom or acyl group, are disclosed. One of the typical compound 3-deoxy-3-(3-tetradecanoyloxytetradecanoylamino)-1,2:5,6-di-O-isopropylidene- α-D-allofuranose is prepared by reacting 3-tetradecanoyloxytetradecanoic acid and 3-amino-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose in the presence of N,N'-dicyclohexylcarbodiimide, as a dehydrating agent. The compound has an excellent carcinostatic activity. |