| abstract |
A fluidized granulating and coating apparatus having a cylindrical treating vessel provided with at least one spray nozzle, at least one air supply duct and one exhaust duct, and a downwardly converging frusto-conical portion. The spray nozzle is disposed at a position below the interface of the fluidized particles within the region of the frusto-conical portion. At least one compressed air nozzle is disposed at a level below the interface of the fluidized particles and within the range of the frusto-conical portion. Disclosed also is a fluidized granulating and coating method which makes use of this apparatus. With the apparatus and the method of the invention, it is possible to produce granular products such as a slow-effecting or long-lasting pharmaceutical product with a high quality and homogeneity at a high yield, by coating cores of spherical granules with a coating composition containing the medical component of the desired property. |