abstract |
The invention provides pure enatiomers of 4,5-disubstituted γ-butyrolactams of the general formula ##STR1## By means of the pure enantiomers of 4,5-disubstituted γ-butyrolactams (I), according to the invention, it is now possible to synthesize (+)-(3R), (4S), (5S), (7R)-3-hydroxy-5-α-hydroxybenzyl-1-methyl-4-phenyl-pyrrolidin-2-one and derivatives in the form of pure enantiomers. |