| abstract |
Compounds of the formula: <IMAGE> in which R is a substituted or unsubstituted monocyclic or bicyclic alkyl group containing from 3 to 8 ring carbon atoms, wherein any substituent is alkyl of 1 to 3 carbon atoms, oxo, hydroxy, carboxy or when the hydroxy and carboxy substituents taken together they form a 1,3-carbonyloxy lactone ring closed structure; n is one of the integers 0, 1, 2 or 3; X is -O-, <IMAGE> or -SO2NH-; and Z is =CH- or -N=; or a pharmaceutically acceptable salt thereof, are anti-hyperglycemic agents. |