| abstract |
Antibiotically active benzazolylthio-carbapenems of the formula <IMAGE> in which R1 represents hydrogen or a hydroxyl-protecting group, R2 represents hydrogen or a carboxyl-protecting group or an ester radical which can be cleaved off in vivo, R3 represents hydrogen or C1-C10-alkyl, C6-C12-aryl or C7-C14-aralkyl, R4 represents hydrogen or represents C1-C10-alkyl, C6-C12-aryl or C7-C14 aralkyl, or represents C1-C10-alkylsulphonyl, C6-C12-arylsulphonyl or C7-C14-aralkylsulphonyl, or represents an amino-protecting group, or represents a group of the formula <IMAGE> in which R5, R6 and R8 are indentical or different and denote hydrogen, C1-C10-alkyl, C6-C12-aryl or C7-C14-aralkyl, and X represents O, S, NH or NCH3, or salts thereof. |