http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4837215-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d709e3167fa2f99a1803c9cfeb0aca63 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 1986-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e59de0e06fd622b109e479a11d46a7a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ade5ee7cb119a68a8f82506a90ee6f20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbec3a0fcb5888b59db84b74fdc0f5d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d12240e9cc7e209f0de0393ee561b15c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72fb1b46dfd55209e99e99b8c78ae889 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3826f927945fd356d580b5ab1ef73d58 |
| publicationDate | 1989-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4837215-A |
| titleOfInvention | Penem derivatives |
| abstract | Compounds of the following formula I <IMAGE> (I) wherein X represents a sulphur or an oxygen atom, R is hydrogen or a C1-C4 alkyl group either unsubstituted or substituted by one or more substituents chosen from a free or protected hydroxy group and halogen atom; A is a Z, Z-O-CO- or -Z-CO- residue, wherein Z represents (a) an optionally substituted phenylene or naphthylene group, (b) an optionally substituted heterocyclediyl radical wherein the hetero ring is mono or bicyclic, saturated or unsaturated containing at least one heteroatom selected from the group of oxygen, sulphur and nitrogen; (c) an optionally substituted linear or branched C1-C7 alkylene radical; (d) a C2-C4 alkenylene or alkynylene group or a group of formula <IMAGE> (e) an optionally substituted C3-C8 cycloalkylene ring; (f) an aralkylene radical of the formula <IMAGE> wherein n is 1, 2 or 3; and Q(+) represents a +NR1R2R3 group, wherein (i) R1, R2, R3, are each independently an optionally substituted alkyl, aralkyl or aryl radical; or p1 (ii) R1 is as defined above under (i) and R2, R3 taken together with the nitrogen atom represent an optionally substituted heterocyclic or fused heterocyclic radical; or (iii) R1, R2, R3, taken together with the nitrogen atom, represent an optionally substituted azoniabicyclo or azoniatricyclo radical; or (iv) R1, R2, R3, taken together with nitrogen atom, represent an optionally substituted pyridinium, pirazinium, pyrazolium, or pyridazinium radical, such radicals being optionally fused with one phenyl ring or with a 5-7 membered, saturated or unsaturated cycloaliphatic or heterocyclic ring, or a pharmaceutically or veterinarily acceptable salt thereof having high antibacterial activity. |
| priorityDate | 1985-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 256.