abstract |
A desintegration tablet contains the filler material in a form and/or size which when coming in contact with water at ambient temperature dissolves so slowly that the water absorption and the action of the desintegration agent are not affected. The grains are either coated with a layer of slowly dissolving substance, in particular a colloid or pseudo-colloid, or consist of a crushed melted substance having a grain size preferably of between 0.2 and 0.6 mm, e.g. mannitol, sorbital and/or xylitol. |