Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_066828a4b6f7a816447cb8ba1bcbb40e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-385 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-21 |
filingDate |
1986-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1989-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0175b00be1d244253094580e58f70b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a864b6a825de199288c649f9efdbac6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51f93030b9a21a2068bfb16a9935abb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e60cf5986e8ab4c903726af945755304 |
publicationDate |
1989-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4831121-A |
titleOfInvention |
Polydisperse native pseudomonas flagellar (H) antigens (FAg) and methods of producing them |
abstract |
PCT No. PCT/AT86/00002 Sec. 371 Date Oct. 2, 1986 Sec. 102(e) Date Oct. 2, 1986 PCT Filed Jan. 13, 1986 PCT Pub. No. WO86/03974 PCT Pub. Date Jul. 17, 1986.Polydisperse native Pseudomonas flagellar (H) antigens (FAg) and methods of producing them are described, wherein each monomeric component contains certain amino acids, has a certain N-terminal amino acid sequence and a certain molecular weight and is free from pyrogenic substances. The ratio of the individual amino acids in the flagellar antigen of the individual H-serotypes is stated. For producing the polydisperse native Pseudomonas flagellar (H) antigens (FAg) methods are indicated, wherein Pseudomonas aeruginosa bacterial cultures or fractions thereof are treated with a detergent and the flagellar antigens are separated from the cultures. Prior to treatment or in the presence of the detergent, the bacterial culture is subjected to a shearing procedure, i.e. exposed to shearing forces. Thereafter, the flagellar antigens separated from the bacterial mass are isolated by a chromatographic treatment. For this chromatographic treatment a molecular sieve can be used and a further purification by chromatography on a column can be carried out for obtaining flagellar antigens of high purity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009214575-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010239583-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5324511-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8173130-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5237053-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263078-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4994161-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009191208-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4946677-A |
priorityDate |
1985-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |