http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4826981-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5abf9edac4452b76815dd883cd24f15 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 |
| filingDate | 1987-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_384aaf3ab9792f41ef76d4f9b810945c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bac5ecbb2bb6c9806fc449f0054b8c96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a21ef1694f1b7c3c56b636c0fe652eb |
| publicationDate | 1989-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4826981-A |
| titleOfInvention | Process for preparing 9-(2-hydroxyethoxymethyl)-guanine |
| abstract | There is disclosed a process for preparing 9-(2-hydroxyethoxymethyl)-guanine (acyclovir) of the formula IV ##STR1## wherein a novel compound of the formula I ##STR2## wherein R and R' may be the same or different and represent hydrogen, (C 1 -C 8 )acyl or benzyl and R 1 represents (C 1 -C 8 )acyl, is hydrolyzed basic conditions. Also disclosed is the novel compound of the formula I, a process for the preparation thereof by condensing a novel compound of the formula II ##STR3## with a compound A--CH 2 --O--CH 2 CH 2 --OR' (A is a leaving group, Q is hydrogen or a leaving group), the novel compound of the formula II and a process for the preparation thereof by means of condensing glyoxal hydrate and a compound of the formula V ##STR4## |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5225550-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4916225-A |
| priorityDate | 1984-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.