| abstract |
Ergolinyl compounds which are nitrogen-substituted in the 8-position and have Formula (I) ##STR1## and physiologically compatible salts thereof, wherein (a) R 1 is hydrogen, the 8-substituent can be in the α- or β-position and ##STR2## represents a single or a double bond, R 2 is hydrogen, C 1-4 -alkyl or C 1-7 -acyl, n R 3 is hydrogen, chlorine or bromine, and n R 4 is C 1-6 -alkyl, C 3-6 -cycloalkyl-C 1-3 -alkyl, C 3-6 -alkenyl, or C 3-6 -alkynyl; or n (b) R 1 is ##STR3## and the 8-substituent can be in the α- or β-position, ##STR4## represents a single or double bond, R 2 , R 3 are as defined above, n R 4 , is C 1 ∝6 -alkyl, C 3-6 -cycloalkyl-C 1-3 -alkyl, C 3-6 -alkenyl, or C 3-6 -alkynyl; and n R 5 is hydrogen, C -10 -alkyl, C 3-10 -alkenyl, or C 3-10 -alkynyl, and n R 6 is C 1-10 -alkyl, C 3-10 -alkenyl, C 3-10 -alkynyl, or aryl, or n R 5 and R 6 together with the connecting N-atom form a 5- to 10-membered heterocyclic ring, preferably 5- or 6-membered, which optionally can contain further heteroatoms. |