abstract |
New bicyclic compounds, inclusive of salts thereof, of the formula: ##STR1## wherein R 1 and R 2 are the same or different and each represents hydrogen, hydroxyl or lower alkoxy, R 3 is hydrogen or lower alkyl, R 4 is hydrogen, lower alkyl, amino-lower-alkyl or acylamino-lower-alkyl, R 5 is hydrogen, lower alkyl or aralkyl which may be substituted, R 6 is hydroxyl, lower alkoxy, amino or lower alkylamino, and m and n each means 1 or 2, have inhibitory activities of angiotensin converting enzyme and bradykinin decomposing enzyme, and are useful as antihypertensive agents. |