http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4818754-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8659631bf38b3a590c0d3edc265492c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 1987-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0ab4dab125161c75e22e755ff0bde8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9d4d35d611b4b79f23fa7289acda10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39bc3293b33dd6ce3dc10f5fe992207a |
| publicationDate | 1989-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4818754-A |
| titleOfInvention | Certain anti-inflammatory pyrazolo [4,3-b] pyridine 7-amines |
| abstract | A compound of the formula (1) or a salt or solvate thereof: <IMAGE> (I) in which: R0 is hydrogen or C1-6 alkyl; R1 and R2 are both hydrogen; or R1 is hydrogen, C1-6 alkyl; and R2 is CN; CR5R6Y where R5 and R6 are independently selected from hydrogen and C1-4 alkyl and Y is selected from hydrogen, OR7 or SR7 where R7 is hydrogen, C1-4 alkyl or C2-4 alkanoyl, and NR8R9 where R8 and R9 are independently hydrogen, C1-4 alkyl, C2-4 alkenyl or C2-4 alkanoyl or together are C4-6 polymethylene; or COR10 is OH or C1-4 alkyl, or COR10 is a pharmaceutically acceptable ester or amide; or R2 is hydrogen, C1-6 alkyl, or phenyl optionally substituted by halogen, CF3, C1-4 alkoxy or C1-4 alkyl; and R1 is CN, CR5R6Y or COR10 as defined for R2 above; or R1 and R2 together form C3-C6 polymethylene optionally substituted by C1-C4 alkyl; R3 is -(CH2)nCO2R11, -(CH2)nCONR12R13,-(CH2)nCN, -(CH2)mNHCOR14, <IMAGE> <IMAGE> where a, b, n, m and p are integers and n is 1 to 10, m is 2 to 10, p is 3 to 5, a is 1 to 3, and b is 1 to 3, and R11 is hydrogen, C1-8 alkyl, benzyl or phenyl, R12 and R13 are independently hydrogen, C1-6 alkyl, benzyl or phenyl, or together form C3-8 alkylene, R14 is C1-4 alkyl, benzyl or phenyl and X is oxygen, sulphur, NH or N-C1-4 alkyl, and R4 is hydrogen; or C1-4 alkyl or benzyl optionally substituted in the phenyl ring by one or two of halogen, CF3, C1-4 alkoxy or C1-4 alkyl, and is attached at nitrogen atom 1 or 2, a process for its preparation and its use as a pharmaceutical. |
| priorityDate | 1986-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 362.