| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
| filingDate |
1986-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73d21addfc4762ee1653c008d1d87973
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e79139defc78f7f471b2752cca64d782
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_955a6b6e18e1d29468839f964237a869 |
| publicationDate |
1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4816564-A |
| titleOfInvention |
Method for producing hepatitis B virus proteins in yeast |
| abstract |
The entire hepatitis B Virus pre-S antigen gene linked in one contiguous reading frame to the hepatitis B virus surface antigen gene has been expressed in Saccharomyces cerevisiae. The expressed protein aggregates into a particulate form which displays the major antigenic sites encoded by both domains, thereby highlighting the utility of yeast as a host for the expression of pre-S domains. This protein is useful in in vitro diagnostic systems and as a vaccine for the treatment and prevention of hepatitis B virus-induced diseases and/or infections. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5158769-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5614384-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5204096-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5098704-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6072049-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6589530-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5747294-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5565548-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5274081-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5576175-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5340575-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5102989-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6100065-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9213951-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6110706-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6117653-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5019386-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5133961-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5650296-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5620844-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003235591-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5670630-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6022543-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6020167-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6197301-B1 |
| priorityDate |
1986-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |