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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02
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filingDate 1987-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1989-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50d832870cc3a64b689a97fb7c6c427a
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publicationDate 1989-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4810816-A
titleOfInvention Process for the production of n-formyl-aspartyl-phenylalanine or its methyl ester
abstract A process for producing N-formyl-aspartylphenylalanine or its methyl ester, wherein aspartic acid is reacted with formic acid and acetic anhydride in approximately stoichiometric quantities in the presence or absence of a catalyst and phenylalanine or its methyl ester is directly added to the dehydration mixture. This process has a higher yield of the desired N-formyl-dipeptide and minimizes the amount of by-products and unreacted starting materials.
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