| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7c855646bca49484c17c3b3ea52aed5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C381-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-15 |
| filingDate |
1987-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe7dc32644a24f5608ee79f9ef746d14 |
| publicationDate |
1989-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4806528-A |
| titleOfInvention |
Process for the preparation of 2-(2-chloroethoxy)-benzenesulfonamide |
| abstract |
In accordance with a novel process, 2-(2-chloroethoxy)-benzene-sulfonamide of formula I ##STR1## is prepared by etherification of 4-chlorophenol of formula II ##STR2## with ethylene carbonate and chlorination of the resulting 2-(2-hydroxyethoxy)-chlorobenzene of formula III ##STR3## with phosgene to give 2-(2-chloroethoxy)-chlorobenzene of formula IV ##STR4## which is converted with chlorosulfonic acid ClSO 3 H and sodium hydroxide to the sulfonic acid sodium salt of formula V ##STR5## which is hydrogenated to the compound of formula VI ##STR6## which is subsequently reacted with phosgene to the sulfonic acid chloride of formula VII ##STR7## which is reacted with ammonia to the sulfonamide of formula I. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006270719-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4959501-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5359135-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008176916-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004082630-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7659293-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7112611-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103508968-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103508968-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7291634-B2 |
| priorityDate |
1987-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |