| abstract |
Cation-exchange support materials and methods for producing such materials are disclosed. In making the support materials, first a thin layer of an adsorbate comprising amine groups is adsorbed to an inorganic support material such as silica, alumina or titania. The adsorbed coating is then optionally crosslinked by a crosslinking agent such as epoxy resin or alkyl bromide. At least one amine group of the adsorbed crosslinked coating is then reacted, preferably in the presence of a proton scavenger, with an amount of a hydrophilic reagent sufficient to generate at least one carboxyl group. Alternatively, amine groups of the uncrosslinked adsorbed coating are reacted, preferably in the presence of a proton scavenger, with an amount of a hydrophilic polyfunctional reagent sufficient to simultaneously crosslink said coating and generate carboxyl groups. |