http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4792562-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12ebbccf13fdf78bd50c9633c103d352 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 1986-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f2dc4c06fc3bb810d30c6e7a6001e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bba671aef43e5e90cf4577f0e4c664de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59b3d697dabef15532dfd6dbe2a4d152 |
| publicationDate | 1988-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4792562-A |
| titleOfInvention | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity |
| abstract | There are disclosed novel compounds of the formula <IMAGE> where n is 0 or 1; R is hydrogen or loweralkyl; R1 is hydrogen, loweralkyl, halogen, cyano, loweralkanoyl, arylloweralkanoyl, aroyl, -CH(OH)R4, -C(OH)R4R5 or -CH2OR5, -CH=CR6R7, -CH=CHCN, -CH=CHOCH3, -CH=CHCO2C2H5, <IMAGE> +TR <IMAGE> -CH2CHR6R7, -CH2CH2CN, -CH2CH2OCH3, -CH2CH2CO2C2H5, <IMAGE> +TR <IMAGE> R4 being hydrogen, loweralkyl, arylloweralkyl or aryl, R5 being loweralkyl, aryl or arylloweralkyl, R6 being hydrogen or loweralkyl and R7 being hydrogen, loweralkyl or aryl; R2 is hydrogen, loweralkyl, loweralkenyl, loweralkynyl, -CH2CO2C2H5, arylloweralkyl, phenyl, nitrophenyl, cyanophenyl, trifluoromethylphenyl, aminophenyl, loweralkanoylaminophenyl, loweralkoxycarbonyl, arylloweralkoxycarbonyl, aryloxycarbonyl, loweralkylaminocarbonyl, arylloweralkylaminocarbonyl, arylaminocarbonyl, alkanoyl, arylloweralkanoyl, aroyl, alkenoyl, alkynoyl, -CH2C 3BOND CCH2-NR'R'', -CH2CH=CHCH2-NR'R'' or -CH2CH2CH2CH2-NR'R'', R' and R'' being independently loweralkyl or -NR'R'' taken as a whole being <IMAGE> and R3 is hydrogen, NO2, NH2, halogen, loweralkanoylamino, arylloweralkanoylamino, aroylamino or loweralkyl; with the proviso that when n is 0, R2 is phenyl, R3 is hydrogen and the pyridine moiety is 2-pyridinyl, R and R1 may not be 2-methyl and 5-methyl; or pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory, methods for synthesizing them, pharmaceutical compositions comprising an effective memory enhancing amount of such a compound and a method of treating a patient in need of memory enhancement which comprises administering such a compound to the patient. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4983608-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4868190-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4916135-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-626450-B2 |
| priorityDate | 1985-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 593.