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filingDate 1985-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1988-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1988-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4788216-A
titleOfInvention Medicinal uses for podophyllotoxins
abstract PCT No. PCT/SE85/00541 Sec. 371 Date Aug. 28, 1986 Sec. 102(e) Date Aug. 28, 1986 PCT Filed Dec. 20, 1985 PCT Pub. No. WO86/04062 PCT Pub. Date Jul. 17, 1986.The invention relates to compounds consisting of podophyllotoxin and its derivatives of the formula <IMAGE> wherein R1 is H or OH and R2 is H or CH3, for treatment of psoriasis, malaria and rheumatoid arthritis and to a method for their preparation. Furthermore, the invention concerns the use of the compounds for treatment of said states of illness, as well as the use of said compounds for the preparation of pharmacological compositions for the treatment of said states of illness.
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