| abstract |
Novel α-aryl-α-(ω-aminoalkyl)-α-[hydroxy(aralkyl and cycloalkyl)]acetic acid derivatives and α-aryl-α-(ω-aminoalkyl)-α[alkanoyloxy(aralkyl and cycloalkyl)]acetic acid derivatives, such as N,N-dimethyl-2-(hydroxyphenylmethyl)-4-dimethylamino-2-phenylbutanamide, 2-(hydroxyphenylmethyl)-5-dimethylamino-2-phenylpentanenitrile, ethyl 2-(hydroxyphenylmethyl)-5-dimethylamino-2-phenylpentanoate, and N,N-dimethyl-2[(acetyloxy)phenylmethyl]-4-dimethylamino-2-phenylbutanamide, useful in the treatment of cardiovascular disease. |