http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4772719-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36089addd8e49e968b4c7e13c517dd1c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-18 |
filingDate | 1985-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1988-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f033ae37c81303d41d02fb20cdfec55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc3a347e4d826fa30c89b199ad15b6e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0acb4f1a99070a6fcff8ad0f22e93bc |
publicationDate | 1988-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4772719-A |
titleOfInvention | Process for the preparation of 3,5-disubstituted isoxazoles |
abstract | PCT No. PCT/EP85/00693 Sec. 371 Date Jul. 24, 1986 Sec. 102(e) Date Jul. 24, 1986 PCT Filed Dec. 10, 1985 PCT Pub. No. WO86/03490 PCT Pub. Date Jun. 19, 1986.A novel process for the preparation of 3-bromo- and 3-chloro-5-substituted isoxazoles is provided. Dibromo- or dichloro-formaldoxime is reacted with an excess of an 1-alkyne derivative of the formula R-C 3BOND CH where R is hydrogen, phenyl or 1-6 C alkyl optionally substituted by halogen, OH, OR', CHO, COR', COOR', CONH2, CONR'R'' or NHCOR' where, in turn, R' and R'', which may be the same or different, are a 1-6 C alkyl or haloalkyl, in the presence of (i) at least an equimolecular amount, with respect to the dibromo- or dichloro-formaldoxime, of an alkaline base selected from the class consisting of sodium and potassium carbonate and bicarbonate and (ii) an inert solvent in which the 1-alkyne is soluble at room temperature. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5489562-A |
priorityDate | 1984-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 208.