| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e52aa637d0639c80e8daa51a74759cbc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
| filingDate |
1985-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1988-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7c10fc565aaebab78050612b060d932 |
| publicationDate |
1988-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4769467-A |
| titleOfInvention |
Fluorogenic 2,1,3-benzoxadiazoles and fluorometric amine/thiol assays therewith |
| abstract |
Fluorogenic compounds are disclosed which are reactive with biologically important analytes including primary amines, secondary amines, and/or thiols and are of the general formula: <IMAGE> wherein X is a group such as <IMAGE> -CN, -CO2CH3, or SO2R, and wherein R is <IMAGE> OR3, or Cl; R1 and R2 are hydrogen atoms or alkyl groups having 1 to 3 carbon atoms and R3 is a phenyl or benzyl group. The inventive compounds form a fluorescent adduct with the above analytes at the number 7 position of the benzoxadiazole ring. The fluorescent adduct thereby formed enables detection of very minute amounts of analyte (picomoles) using conventional fluorescent analytical methods. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10429309-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100425599-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011082354-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8927727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3003145-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6248895-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9588108-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5989840-A |
| priorityDate |
1983-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |