http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4753933-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e759368252958400591adc79b18e9bb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1987-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1988-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2ccb79f0205d88dac2c2c47e286cad4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c267888e3b2cec91f68bd6055951861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9a336dc88eb7671a341937dbe54d61d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d542064110dcbf91a4f4c946d7513431 |
| publicationDate | 1988-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4753933-A |
| titleOfInvention | Anxiolytic amides derived from certain 1,8-naphthyridine-2-amines |
| abstract | The invention provides new substituted amides of formula: R-CONH-Het in which: either R is cycloalkyl (3 to 6 carbons), cyclohexadienyl, phenyl, substituted phenyl or a heterocyclic systems chosen from 3-pyridyl, alkyloxy-3-pyridyl, thienyl, alkylthienyl, furyl, tetrahydropyridyl, pyridazinyl, and alkylpyridazinyl, and Het is 1,8-naphthyridin-2-yl substituted at the 7-position by alkyloxy, alkylthio or alkylsulphinyl, themselves substituted with alkylamino or dialkylamino (in which the alkyl portions can form, with the nitrogen atom, a 5- or 6-membered heterocyclic system optionally containing another hetero atom chosen from O, S or N, and optionally substituted by alkyl) or by dialkylcarbamoyl or N-alkyl-N-(alkyloxycarbonyl)amino, or substituted at the 7-position by dialkylaminovinyl; or R is 4-(alkylamino)phenyl or 4-(alkyloxycarbonylamino)phenyl and Het is 1,8-naphthyridin-2-yl substituted at the 7-position by alkyloxy or alkylthio, the said alkyl radicals and alkyl portions containing 1 to 4 carbons, their salts, their preparations and pharmaceutical compositions which contain them. These new substituted amides are especially active as anxiolytics, hypnotics, anticonvulsants, antiepileptics and muscle relaxants. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6156766-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5258356-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1102615-C |
| priorityDate | 1986-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 469.