Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c3f7ac9513e9ffd299c153d9713f7be |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-28 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- |
filingDate |
1987-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1988-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_083daea34962766a2ad07cdeb025e663 |
publicationDate |
1988-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4731476-A |
titleOfInvention |
Process for the separation of L-leucine and L-isoleucine |
abstract |
The invention relates to a process for the separation of L-leucine and L-isoleucine. The process is carried out by subjecting a mixture of leucine ester, and isoleucine ester, (or a mixture of leucine ester, isoleucine ester and valine ester) to an esterase catalyzed hydrolysis resulting in a selective hydrolysis of the leucine ester. The pure L-leucine can be isolated from the reaction mixture by first removing the non-hydrolyzed esters by extraction with an organic solvent and then crystallizing the L-leucine at its isoelectric point. The recovered L-iso-leucine ester is purified by distillation (if necessary), and hydrolyzed to yield pure crystalline L-isoleucine. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4820869-A |
priorityDate |
1986-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |