abstract |
This invention is concerned with a composition for solid pharmaceutical preparations of active vitamins D3, having the remarkably improved stability of active vitamins D3, and an extremely advantageous process for the preparation thereof from the industrial viewpoint. The composition of this invention is a composition for solid pharmaceutical preparations of active vitamins D3 prepared by forming an outer layer comprising active vitamins D3 and an excipient, which is readily soluble in an organic solvent, around an inner layer comprising an excipient which is slightly soluble in an organic solvent. |