| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a285d8ecd0184a7e5d89a1e4e07997 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C62-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C62-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-367
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C62-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-04 |
| filingDate |
1986-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1988-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5fecbfdbd89ea925f5eb90fe5c88133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51013ea7acc78562dabfbb7f851fcd49 |
| publicationDate |
1988-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4728740-A |
| titleOfInvention |
Intermediates for the production of epipodophylotoxin and related compounds and processes for the preparation and use thereof |
| abstract |
There is provided a novel and efficient stereoselective total synthesis of epipodophyllotoxin and related epipodophyllotoxin compounds of the general formula <IMAGE> wherein R1 and R2 each are independently hydrogen or (lower)alkoxy, or R1 and R2, taken together, is methylenedioxy; R4 and R6 each are independently hydrogen or (lower)alkoxy; and R5 is hydrogen or a phenol-protecting group; or an acid addition salt thereof. The present invention also provides novel intermediates and processes for the preparation of said intermediates, which are then converted into known antineoplastic agents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5003087-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2266607-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5011948-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5338867-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2289549-A2 |
| priorityDate |
1985-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |