http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4709027-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a717ea5b2ac78ac329ab3a9659d834d2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 1986-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1987-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b442a184be09d3702b1465e218fe0e34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_636d9b0127d61f89480666b28c8123cc |
| publicationDate | 1987-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4709027-A |
| titleOfInvention | Bicyclic spirosulfonimides with psychotropic activity |
| abstract | There are disclosed compounds of the formula <IMAGE> wherein R1 and R2 are each, independently, hydrogen or lower alkyl, or R1 and R2 taken together represent <IMAGE> <IMAGE> <IMAGE> <IMAGE> +TR <IMAGE> A is O or NR3; B is -(CH2)n-, <IMAGE> R3 is hydrogen or lower alkyl; R4 is hydrogen, lower alkyl, aryl of 6-12 carbon atoms or halo; R5 is unsubstituted or substituted phenyl, 2-pyridinyl, 2-pyrimidinyl, 2-pyrazinyl or 3-pyridazinyl, where the substituents are selected from the group lower alkyl, lower alkoxy, halo, cyano, nitro and trifluoromethyl; Z is -(CH2)n- or vinylene; X is lower alkylene, vinylene or O; m is 2-5; n is 1-3; o is 1-5; and the pharmaceutically acceptable salts thereof and their use as antipsychotic/anxiolytic agents having a low liability for extrapyramidal side effects. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9851312-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5631017-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5484788-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5637314-A |
| priorityDate | 1986-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.