abstract |
Anti-androgenic composition compound of the formula <IMAGE> (I) wherein Q is CO, CH(OR), CR(OH), or CR (OC)-lower alkyl); R is H, or C1-2-alkyl; X is hydroxyalkyl, methoxy-C2-11-alkyl, ethoxy-C2-11-alkyl or oxo-C2-11-alkyl, formyl-C2-11-alkyl, carboxy-C2-11-alkyl or (C1-2-alkyl) oxycarbonyl-C2-11-alkyl; c is 1 or 2; p or w are 0, 1 or 2 and the sum of p and w is 1 to 4; and a pharmaceutically acceptable salt thereof. |