| abstract |
An active site peptide which blocks immune complex binding to Fc receptors, the peptide having an amino acid sequence selected from the group consisting of: A-B-C-D-E-F-G-H-I-J-K-L-M-N-O-P, or a subgroup thereof, wherein A is Arg, Lys, Orn, Gln, or His; B is Ser, Thr, Ala, or Gly; C is Thr, Ser, Ala, or Gly; D is Thr, Ser, Ala, or Gly; E is Lys, Arg, Orn or His; F is Thr, Ser, Ala, or Gly; G is Ser, Thr, Ala, or Gly; H is Gly, Ala, Thr, Ser, Lys, Arg, or Orn I is Pro, Val, Leu, Ile, or Ala; J is Arg, Lys, Orn, or His; K is Ala, Thr, Ser, or Gly; L is Ala, Thr, Ser, or Gly; M is Pro, Val, Leu, Ile, or Ala; N is Glu, or Asp; O is Val, Leu, Ile, or Ala; P is Tyr, or Phe. and pharmaceutically acceptable salts thereof. |