Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc2a22a9271507062ad7e07974d3c58 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-55 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-55 |
filingDate |
1984-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1987-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e17b4eb5da3cff08e2d7ea92a70b376a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe8f00dbb4cc98dd88d0193887749d65 |
publicationDate |
1987-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4675383-A |
titleOfInvention |
Purification of T-cell growth factor |
abstract |
Substantially homogenous T-cell growth factor is isolated. A multiple-step purification procedure of T-cell growth factor-containing biological sample includes at least one reverse-phase HPLC fractionation using a C3 to C5 silica gel stationary phase. A preferred pre-purification protocol includes concentration of the biological sample on a semipermeable medium followed by gel filtration and semi-preparative reverse-phase HPLC on a hydrophobic stationary phase. Fractionating the pre-purified biological sample with two or three reverse-phase HPLC fractionations using C3 to C5 silica gel stationary phase yields T-cells growth factor of over 90% purity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0366532-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5902490-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4908433-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6010633-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4908434-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5614185-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5417970-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7125492-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5359035-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5419899-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0368711-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4730036-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4925919-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4808151-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005011836-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6015500-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6251292-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9004406-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5472605-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9004642-A1 |
priorityDate |
1983-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |