http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4670251-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_309d0fb5c7d9bf27a5eff6ed2fd4a5df |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2063 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 1984-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1987-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e532dac69fdd66844edaab262c68949 |
| publicationDate | 1987-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4670251-A |
| titleOfInvention | Microcrystalline tableting excipient derived from whey |
| abstract | A solid pharmaceutical composition suitable for oral or rectal administration comprising a unit dosage of a pharmaceutically active ingredient (and optionally one or more inert fillers) homogeneously dispersed in a pharmaceutically acceptable binder, wherein at least a major portion (i.e., at least 50% by weight) of the binder is a microcrystalline solid phase prepared by raising the pH of a dairy whey lactose permeate having a pH below about 7 to a pH between about 8 and 10 to form (i) a lactose-rich aqueous solute phase capable of being autoclaved for 10-20 minutes at 121 DEG C. and 15 psi to form a clear, light-colored solute having a pH of about 7; and (ii) a microcrystalline solid phase which contains substantially all of the dissolved solids from said solute phase which would form a precipitate upon autoclaving said solid phase; separating the microcrystalline solid phase from the solute phase; and drying the separated microcrystalline solid phase to form a nontoxic, tasteless, odorless, chalky white free-flowing powder. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9001879-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007190130-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5650184-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9007541-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4894236-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4904477-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0412877-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008102130-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109601872-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5032415-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9219228-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011165237-A1 |
| priorityDate | 1984-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.