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filingDate 1985-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26bf441a0dc1de68bbe393349e1c076d
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publicationDate 1987-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-4661487-A
titleOfInvention Process for reducing reflex tachycardia in the treatment of hypertension employing a combination of a diazacyclopentene derivative and a pyridazinone derivative
abstract The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (+/-)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl)-phenyl]-5-methyl-3(2H)-pyridazinone or 4,5-dihydro-6-[4-(1-imidazolyl)-thien-2-yl]-5-methyl-3(2H)-pyridazinone, on the other side, as the active substances.
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