Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-23 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-23 |
filingDate |
1985-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1987-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a687be17d43398f8deb44e6d3375eec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6801730ef73ad86d7a9c48785bd828e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f72dcb31af1a2e209daf01ac3760ea7 |
publicationDate |
1987-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-4656247-A |
titleOfInvention |
Effective hormonal peptides: D-3-QA1 6-LHRH |
abstract |
Two sets of hormonal peptides are synthesized which are super agonists of the lutenizing hormone releasing hormone (LHRH). Chronic administration results in the inhibition of LHRH which is responsible for stimulating cell growth in the testes. One peptide has the D(dextro)-form of a mono-heterocyclic amino acid in position six (D-3-pyridyl-alanine) while the other peptide has a bi-heterocyclic amino acid in that same position ( beta -(3-quinolyl)-D- alpha -alanine. Both peptides are less metabolically reactive than those in the prior art and yet both peptides are significantly more potent than LHRH itself. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241842-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004265285-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004132179-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003040482-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003015579-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004259803-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006229251-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5843901-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7071165-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008279812-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2161037-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6455499-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5212288-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005020524-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004258672-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007274946-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2662087-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006088512-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6423686-B1 |
priorityDate |
1985-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |