http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4642205-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e752c83f437681dc056d7e37f070dec3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 |
filingDate | 1985-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1987-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c341753350e360f19ae88ac1c17f92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5c4c6a948d6161f53f415b1383d9539 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2910dd41792a05792eea2e61cf757345 |
publicationDate | 1987-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-4642205-A |
titleOfInvention | Diastereomer salts of phenylalanine and N-acyl derivatives thereof and process for the separation of optically active phenylalanine and N-acyl derivatives thereof |
abstract | The present invention relates to the separation of optically active phenylalanine and N-acyl derivatives thereof and novel diastereomer salts of the said compounds. n According to the invention a racemic compound of the formula ##STR1## is reacted with an optically active resolving agent of the formula ##STR2## in a polar solvent and/or a mixture of solvents comprising at least one apolar solvent and optionally an achiral acid or base, thereafter n (a) when using the D-isomer of the resolving agent of the formula II, the crystalline diastereomer salt formed with the L-isomer of the compound of the formula I is separated, or n (b) when using the L-isomer of the resolving agent of the formula II, the crystalline diastereomer salt formed with the D-isomer of the compound of the formula I is separated, and n the enantiomers of the compound of the formula I from the diastereomer salt or the mother liquor are liberated by the aid of an achiral acid or base and the optically active product is separated in crystalline form. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6235927-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6465684-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5041637-A |
priorityDate | 1984-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 181.