| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
| filingDate |
1986-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1987-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b92f9f2b4a04025f5905b206b2d734e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d8baf8e06060c989f0d3dabc7d8a120 |
| publicationDate |
1987-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4640930-A |
| titleOfInvention |
Naphtho(1,8-bc)-1,5-thiazocinones |
| abstract |
A compound of the formula ##STR1## wherein R 1 is phenyl substituted with 1 to 3 lower alkoxy groups, or 1 to 3 halogens; R 2 is hydroxy or lower alkanoyloxy; R 3 and R 4 are each independently lower alkyl or together form a pyrrolidine or piperidine ring; and n is 2 to 4, and pharmaceutically acceptable acid addition salts thereof are described. The compounds of formula I are active as calcium channel blockers and accordingly, are useful as agents for lowering blood pressure, and as agents for treating ischemia. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6541479-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002115655-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6951860-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5008411-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0394026-A1 |
| priorityDate |
1986-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |